Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4595)
Related Products (4595)
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DSPE-PEG2000-iRGD
0 ImagesCat. No.: HY-172494DSPE-PEG2000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG2000-iRGD can be used for agent delivery.
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L-Ribose
0 ImagesL-Ribose is the enantiomer of D-ribose (HY-113375). L-Ribose replaces D-ribose to synthesize L-ribonucleic acid in cells, leading to erroneous gene transcription. L-Ribose serves as a starting material for L-nucleoside analogs, glycoconjugates and oligonucleotides. L-Ribose can be used in research related to hepatitis B virus infection, hepatitis C virus infection, hepatitis D virus infection, Epstein-Barr virus infection and cytomegalovirus infection.
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5-Bromoindolin-2-one
0 ImagesSynonyms: 5-Bromooxindole5-Bromoindolin-2-one (5-Bromooxindole) is a synthetic intermediate. 5-Bromoindolin-2-one can be used for the synthesis of CDK2 inhibitors and antibacterial agents.
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Pyridin-4-ol
0 ImagesPyridin-4-ol is a pyridinol and can be used as synthetic intermediate.
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Chloramphenicol succinate sodium
0 ImagesChloramphenicol succinate sodium is a prodrug of Chloramphenicol (HY-B0239), acting as a P2Y14R inhibitor with an IC50 of 1.585 nM. Chloramphenicol succinate sodium serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may account for its toxicity. Chloramphenicol succinate sodium exerts a significant inhibitory effect on colitis. Chloramphenicol succinate sodium can be used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis and inflammatory bowel disease.
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Thalidomide-5-Br
0 ImagesThalidomide-5-Br is an analog of Thalidomide (HY-14658). Thalidomide-5-Br serves as an intermediate for research related to the generation of Thalidomide derivatives.
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Quinoline-2-carboxaldehyde
0 ImagesSynonyms: 2-QuinolinecarboxaldehydeQuinoline-2-carboxaldehyde (2-Quinolinecarboxaldehyde) is a quinoline derivative that serves as a synthetic precursor for Schiff base copper complexes. Quinoline-2-carboxaldehyde is applicable to research related to the synthetic design of biomaterials or organic compounds, such as fluorescent sensors.
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2,4-Dihydroxybenzaldehyde
0 Images2,4-Dihydroxybenzaldehyde is an endogenous metabolite. 2,4-Dihydroxybenzaldehyde is a pharmaceutical intermediate that can be used to synthesize various Schiff base compounds. 2,4-Dihydroxybenzaldehyde exhibits significant anti angiogenic, anti-inflammatory, and analgesic activities. 2,4-Dihydroxybenzaldehyde reduces the production of NO and ROS by inhibiting the expression of iNOS and COX-2. 2,4-Dihydroxybenzaldehyde is commonly used in the study of inflammatory conditions.
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(S)-tert-Butyl 6-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate
![(S)-tert-Butyl 6-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate](https://file.medchemexpress.com/product_pic/hy-w071588.gif "Click to View (S)-tert-Butyl 6-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate Product Detail")
0 ImagesCat. No.: HY-W071588CAS No.: 1262397-12-5(S)-tert-Butyl 6-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate is a drug intermediate for synthesis of various active compounds.
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N1,N1-Dimethylpropane-1,2-diamine dihydrochloride
0 ImagesCat. No.: HY-32007ACAS No.: 75975-34-7N1,N1-Dimethylpropane-1,2-diamine dihydrochloride is a drug intermediate for synthesis of various active compounds.
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tert-Butyl 4,4,4-trifluorobut-2-enoate
0 Imagestert-Butyl 4,4,4-trifluorobut-2-enoate is a drug intermediate for synthesis of various active compounds.
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5-(4-Isopropylpiperazin-1-yl)pyridin-2-amine
0 Images5-(4-Isopropylpiperazin-1-yl)pyridin-2-amine is a drug intermediate for synthesis of various active compounds.
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4-Fluorobenzoic acid
0 Images4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity.
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(2S)-1-[(tert-Butoxy)carbonyl]-2-methylazetidine-2-carboxylic acid
![(2S)-1-[(tert-Butoxy)carbonyl]-2-methylazetidine-2-carboxylic acid](https://file.medchemexpress.com/product_pic/hy-w063820.gif "Click to View (2S)-1-[(tert-Butoxy)carbonyl]-2-methylazetidine-2-carboxylic acid Product Detail")
0 ImagesCat. No.: HY-W063820CAS No.: 1363402-35-0(2S)-1-[(tert-Butoxy)carbonyl]-2-methylazetidine-2-carboxylic acid is a drug intermediate for synthesis of various active compounds.
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Benzyl methyl(2-(methylamino)ethyl)carbamate
0 ImagesBenzyl methyl(2-(methylamino)ethyl)carbamate is a drug intermediate for synthesis of various active compounds.
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2,5-Dimethoxypyridine
0 Images2,5-Dimethoxypyridine is a drug intermediate for synthesis of various active compounds.
